Description

Indications

Congestive heart failure, cardiac tachyarrhythmias (Paroxysmal supraventricular tachycardia, atrial flutter & fibrillation).

Dosages

Initially 0.25-1.5 mg daily. Maint; 0.25-0,5 mg
daily Children : Initially 10-20 mcg/kg body wt. 6 hrly. Maint 10-20 mcg/kg body wt. in single or divided doses daily.

Contra-indications

Hypokalemia, ventricular tachycardia, partial A.V. block, acute myocarditis. Wolf-Parkinson White Syndrome.

Special Precautions

Elderly, renal or severe hepatic disease, myocardial infarction, thyrotoxicosis, calcium synergises to precipitate toxicity. Pediatrics: Reduce dose necessary. Pregnancy: No evidence of risk. Lactation: Present in breast milk hence use only if indicated.

Side-effects

Anorexia, nausea, vomiting, abdominal pain, fatigue, headache, mental confusion, restlessness

Drug interactions

Diuretics causes hypokalemia and precipitate digitalis toxicity. Blood levels increased by calcium channel blockers, spironolactone, guanidine and calcium salts. Metoclopramide interferes with absorption of solid dosage form of digoxin, Antacids reduces digoxin absorption

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